Low Incidence of Skin Infections
In 2 open-label, non-comparative, multicenter, long-term studies evaluating atopic dermatitis (AD) patients treated with Protopic Ointment, including:
- A study of nearly 8,000 patients21
- 3,964 adults
- 3,959 children (2 to 15 years of age)
- A study of up to 4 years duration20
- 408 adults
- 391 children (2 to 15 years of age)
The incidence of skin infections was low in both studies.20,21
- Consistent with previous reports of skin infections in patients with AD
- Consistent with previous studies in eczema patients treated with Protopic24

Skin infections should be cleared prior to application, and there may be an increased risk of certain skin infections.
