A Safe and Effective Eczema
Treatment Alternative
Protopic Ointment is a safe and well-tolerated alternative when other topical prescription treatments are inadequate or not advisable:
- More than 20,000 eczema patients, including 8,000 children studied4
- More than 3 years of follow-up in long-term safety studies
- Skin burning and pruritus—the 2 most common application site events—generally decreased over time:12,20,21
- Correlated with baseline disease severity and extent
- Occurred primarily at the beginning of therapy
- Generally resolved within a few days
- Minimal systemic absorption and no systemic accumulation7
- Incidence of skin infections was low 20,21
- No impairment of vaccine response in treated pediatric patients treated with the following:7,22,23
- Pneumococcal polysaccharide
- Meningococcal serogroup C
Important Safety Information
WARNING: Long-term safety of topical calcineurin inhibitors has not been established (beyond 1 year of non-continuous use). Although a causal relationship has not been established, rare cases of malignancy (e.g., skin and lymphoma) have been reported in patients treated with topical calcineurin inhibitors, including Protopic. Therefore, continuous long-term use of topical calcineurin inhibitors, including Protopic, in any age group should be avoided and application limited to areas of involvement with atopic dermatitis. The diagnosis of atopic dermatitis should be confirmed if signs and symptoms do not improve within 6 weeks.
Skin infection should be cleared prior to application, and there may be an increased risk of certain skin infections.